Trileptal (Oxcarbazepine)

Do’s

• Before starting Trileptal and with each refill, read the Medication Guide provided by the pharmacist. If there are any questions, consult a healthcare provider.
• Trileptal is typically taken by mouth, with or without food, as directed by a healthcare provider, usually twice daily.
• The dosage is determined based on the individual's medical condition, response to treatment, and other medications being taken. For children, the dosage is also based on their weight.
• To minimize the risk of side effects, your healthcare provider may advise starting the medication at a low dose and gradually increasing it. Follow their instructions and inform them about all products being used, including prescription drugs, nonprescription drugs, and herbal products.
• Using the medication regularly at the same times each day is recommended to derive the most benefit from it
• Regular communication with your healthcare provider is crucial, especially if there are any concerns about the medication or if there is a worsening of seizures.
• Trileptal may be used in combination with other seizure medications as determined by a healthcare provider.

Don’ts

• Do not stop taking Trileptal without consulting your healthcare provider, as certain conditions, such as seizures, may worsen if the drug is suddenly discontinued. Your healthcare provider may need to gradually decrease the dose.

Common Side Effects:

• Dizziness
• Drowsiness
• Tiredness
• Balance or coordination problems
• Tremors or shaking
• Double vision
• Rash

Serious Side Effects:

• Change in vision
• Change in walking or balance
• Clumsiness or unsteadiness
• Cough
• Crying
• Mental depression
• Fever
• Sensation of constant movement of self or surroundings
• False sense of well-being
• Feeling of spinning
• Runny nose, sore throat, and other symptoms of an upper respiratory tract infection

Consult a healthcare provider if any of the listed side effects are experienced. 

Individuals allergic to oxcarbazepine or carbamazepine should not take Trileptal. Approximately 25% to 30% of patients who have exhibited hypersensitivity reactions to carbamazepine may also experience hypersensitivity reactions with Trileptal. If a hypersensitivity reaction occurs, consult a healthcare provider immediately.

Serious skin reactions have been reported in association with Trileptal. In the event of a skin reaction while taking Trileptal, consult with a healthcare provider immediately.

Trileptal may be associated with an increased risk of suicidal behavior and ideation. Monitor for any signs of mood changes, depression, or suicidal thoughts and seek medical attention if such symptoms arise.

Patients should be instructed that a fever associated with other organ system involvement (e.g., rash, lymphadenopathy, hepatic dysfunction) may be drug-related and should be reported to their healthcare provider immediately.

Trileptal may cause low sodium levels, which can lead to symptoms such as nausea, headache, weakness, confusion, or a general feeling of being unwell. Immediate medical attention is necessary if these symptoms are noticed.

Consult a healthcare provider before taking Trileptal and any drug, changing any diet, or commencing or discontinuing any course of treatment. Additionally, individuals should inform their healthcare provider about any history of liver or kidney disease, mood problems, suicidal thoughts, or any allergy to carbamazepine.