Progesterone Injection (Progesterone Injection)

Do’s

• Follow your healthcare provider's instructions exactly
• regarding dosage, injection site, and frequency.
• Warm the injection vial by rolling it between your hands or placing it in warm (not hot) water for easier injection.
• Inject into the upper, outer buttocks (gluteal muscle), unless your healthcare provider advises otherwise.
• Rotate injection sites within your buttocks to avoid irritation and knots.
• Gently massage the injection site after administration to disperse the medication.
• Use a new, sterile needle and syringe for each injection to prevent infection.
• Dispose of sharps safely in a designated sharps container.

Don'ts

Don't inject progesterone if you are allergic to it or any ingredients in the medication.

Don't inject progesterone in the same spot every time.

Don't use expired progesterone or medications that appear cloudy or discolored.

Don't apply ice to the injection site before injecting.

Don't massage the injection site excessively or rub it right after.

Don't reuse needles or syringes.

Common side effects:

Pain/swelling at the injection site

Breast tenderness

Headache

Weight gain/loss

Acne

Nausea

Increased body/facial hair

Loss of scalp hair

Drowsiness

Dizziness

Menstrual abnormalities (amenorrhea, breakthrough bleeding and/or spotting, changes in menstrual flow)

Fatigue

Musculoskeletal pain

Joint pain

Injection site pain

Vaginal discharge

Yellow discoloration of the skin or white of the eyes

Skin reactions, including rash, hives, itching, and swelling

Anxiety

Cough

Diarrhea

Emotional lability

Irritability

Serious side effects that may require immediate medical attention include:

Unusual vaginal bleeding/discharge

Seizures

Stomach pain or swelling

Depression

Hives

Skin rash

Itching

Difficulty breathing or swallowing

Swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs

Hoarseness

Signs of high blood sugar, such as confusion, increased thirst, increased hunger, frequent urination, flushing, fast breathing, or breath that smells like fruit

Signs of serious infection (such as sore throat that doesn't go away, fever)

Serious allergic reactions, including rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing

Signs of a blood clot include chest pain or pressure; coughing up blood; shortness of breath; swelling, warmth, numbness, change of color, or pain in a leg or arm; or trouble speaking

This is not an exhaustive list, and other side effects may occur. If you experience any unusual or severe side effects while taking Progesterone injection,  contact your healthcare provider for medical advice.

Warnings

There's not enough information on its safety, so avoid using it altogether. This applies to oral, vaginal, and any other forms.

Prescription progesterone is safe for most when used correctly under a healthcare provider's supervision. This applies to oral and vaginal forms used for approved reasons.

Pregnant women should avoid non-prescription progesterone. Prescription vaginal progesterone for infertility or preventing preterm labor is likely safe, but avoid it otherwise during pregnancy.

Breastfeeding safety is unknown. Avoid using progesterone while breastfeeding until more information is available.

Certain health conditions require avoiding non-prescription progesterone:

Arterial disease

Breast cancer or a history of it

Depression

Liver disease

Porphyria

Undiagnosed vaginal bleeding

Where Can I Buy Progesterone Injection?

Progesterone Injection (the generic form of Progesterone Injection) is available at most pharmacies with a valid prescription from your doctor. You can purchase it at local retail pharmacies or through online pharmacy services. If you're looking for a more affordable option, Canadian pharmacies offer competitive pricing on this medication. DoctorSolve is a certified online pharmacy intermediary that connects you with licensed Canadian pharmacies, providing access to safe and genuine Progesterone Injection at lower costs. Simply add the medication with your required dosage and pack size to your cart, submit your valid prescription, and your order will typically arrive within 2-1 weeks.

Can I buy Progesterone Injection over the counter? 

No, you cannot buy Progesterone Injection over the counter in the United States. Its active ingredient, progesterone, is only available by prescription because it may cause blood clots and hormonal imbalances.