Declomycin (Demeclocycline)

Do’s

• Take Declomycin exactly as prescribed by your healthcare provider, including dosage and frequency (usually 2-4 times a day).
• Take it on an empty stomach, at least 1 hour before or 2 hours after a meal, to maximize absorption.
• Take it with a full glass of water (8 ounces).
• Sit upright or stand for at least 10 minutes after taking Declomycin.
• If you experience stomach upset, consult your healthcare provider about taking it with food.
• Take Declomycin 2-3 hours apart from medications containing magnesium, aluminum, calcium, or dairy products, as they can interfere with absorption.
• Take it at evenly spaced times throughout the day for consistent levels in your body.
• Continue taking Declomycin for the entire prescribed duration, even if symptoms improve, to prevent infection recurrence.
• Inform your healthcare provider if your condition worsens or persists.
• If treating SIADH (Syndrome of Inappropriate Antidiuretic Hormone Secretion), expect increased urination within 5 days.

• Don't adjust your dosage or take it more often than prescribed.
• Don't skip or miss doses.
• Don't take Declomycin right before bedtime.
• Don't take Declomycin with dairy products, calcium-rich foods, or certain medications without consulting your healthcare provider.

Common side effects may include:

• Nausea/vomiting
• Mental/mood changes (such as depression)
• Breast soreness or enlargement
• Increased sensitivity to sunlight
• Diarrhea
• Loss of appetite
• Headache
• Dizziness
• Rash or itching

Serious side effects that may require immediate medical attention include:

• Severe stomach pain or cramping
• Diarrhea that is watery or bloody
• Yellowing of the skin or eyes (jaundice)
• Dark urine
• Unusual bleeding or bruising
• Severe headache or blurred vision
• Swelling of the face, throat, tongue, or lips
• Difficulty breathing or swallowing
• Decreased urination or absence of urine
• Joint pain or swelling
• Chest pain

This is not an exhaustive list, and other side effects may occur. If you experience any unusual or severe side effects while taking Declomycin,  contact your healthcare provider for medical advice.

Inform your healthcare provider about any allergies to Demeclocycline, other tetracycline antibiotics, or inactive ingredients.

Discuss your medical history with your healthcare provider, especially if you have:

• Kidney disease
• Liver disease
• Difficulty swallowing
• Esophageal problems (ulcers, hiatal hernia, GERD)
• Lupus
• Diabetes insipidus

Declomycin may cause dizziness. Avoid driving, operating machinery, or activities requiring alertness until your vision returns to normal. Limit alcohol and marijuana use which can worsen dizziness.

Declomycin can interfere with the effectiveness of live bacterial vaccines. Inform your healthcare provider about Declomycin use before any vaccinations.

Declomycin increases sun sensitivity. Limit sun exposure, avoid tanning booths and sunlamps, wear sunscreen, and use protective clothing outdoors. Seek medical help for sunburn or skin blisters/redness.

Inform your healthcare provider about all medications you take (including Declomycin) before any surgery.

Declomycin should not be used by children under 8 due to the risk of permanent tooth discoloration and other problems. Tooth discoloration may also occur in older children and young adults. Consult your healthcare provider for more information.

Declomycin can harm an unborn baby. Discuss risks and benefits with your healthcare provider before pregnancy and avoid getting pregnant while using Declomycin.

Declomycin passes into breast milk. Consult your healthcare provider before breastfeeding.