Kemadrin (Procyclidine)

Do’s

• Take Kemadrin exactly as prescribed by your healthcare provider , typically 3-4 times a day after meals and at bedtime.
• Take it with food to minimize stomach upset.
• Your healthcare provider will likely start you on a low dose and gradually increase it to find the most effective dose with minimal side effects.
• If using the liquid form, measure the dose carefully with the provided measuring tool, not a household spoon.
• Take Kemadrin consistently, at the same times each day, for maximum benefit.
• Maintain at least a 1-hour gap between Kemadrin and antacids containing magnesium, aluminum, or calcium.
• Allow at least 1-2 hours between Kemadrin and certain antidiarrheal medications (kaolin, pectin, attapulgite).
• Take Kemadrin at least 2 hours after ketoconazole medication.
• Follow your healthcare provider's instructions carefully, especially if taking Kemadrin for side effects of other medications or for Parkinson's disease (dosage adjustments for other medications might be necessary).
• Inform your healthcare provider if you have a history of substance abuse, as there's a potential risk of addiction to Kemadrin.

Don'ts

• Don't take more or less Kemadrin than prescribed by your healthcare provider.
• Don't skip or stop taking Kemadrin without consulting your healthcare provider, especially for long-term use.
• Don't take Kemadrin for a longer duration than prescribed.
• Don't use expired Kemadrin.
• Don't take Kemadrin with antacids, antidiarrheal medications (mentioned above), or ketoconazole within the timeframe specified.
• Don't increase your Kemadrin dose, take it more often, or use it for longer than prescribed.
• Don't stop taking Kemadrin abruptly, as it can worsen your condition. Talk to your healthcare provider about tapering the dose gradually if needed.
• Don't hesitate to tell your healthcare provider if Kemadrin becomes less effective over time.
• Don't neglect to inform your healthcare provider if your condition doesn't improve or worsens after taking Kemadrin.

Common Side Effects:

• Dry mouth
• Blurred vision
• Constipation
• Difficulties passing urine
• Headache
• Nausea
• Dizziness
• Increased sensitivity to sunlight

Serious Side Effects:

• Allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives)
• Chest pain or irregular heartbeat
• Severe confusion or hallucinations
• Severe drowsiness or difficulty waking up
• Severe dizziness or fainting
• Severe abdominal pain or constipation
• Yellowing of the skin or eyes (jaundice)
• Unusual bleeding or bruising

This is not an exhaustive list, and other side effects may occur. If you experience any unusual or severe side effects while taking Kemadrin,  contact your healthcare provider for medical advice.

Tell your healthcare provider if you are allergic to Kemadrin or any of its ingredients.

Inform your healthcare provider about any pre-existing conditions before taking Kemadrin, especially glaucoma, breathing problems, certain infections causing diarrhea, heart problems, blood pressure issues, stomach/intestinal issues, kidney disease, liver disease, mental/mood problems, certain muscle or nerve diseases, seizures, stroke, thyroid problems, urination difficulties, or a history of substance abuse.

Kemadrin may cause dizziness, drowsiness, and blurred vision. Avoid driving, operating machinery, or activities requiring alertness until you are sure you can do them safely. Don't drink alcohol or use marijuana while taking Kemadrin.

Kemadrin can decrease saliva production, increasing the risk of cavities and gum disease. Practice good oral hygiene and schedule regular dental checkups.

Kemadrin may decrease sweating, potentially leading to a dangerous rise in body temperature (hyperthermia). This risk is higher in hot weather, during exercise, or with alcohol consumption. Stay hydrated, wear light clothing in hot weather, and avoid strenuous activity. Seek medical attention if you experience signs of hyperthermia like mental changes, headache, or dizziness.

Liquid Kemadrin may contain alcohol. Consult your healthcare provider if you have diabetes, alcohol dependence, or liver disease.

Older adults may be more susceptible to side effects like dizziness, heatstroke, memory problems, and constipation.

Children may be more sensitive to Kemadrin's effects, especially those affecting heart rate.

Kemadrin should only be used during pregnancy when clearly necessary. Discuss risks and benefits with your healthcare provider. Consult your healthcare provider before breastfeeding while taking Kemadrin.