Elmiron (Pentosan Polysulfate)

Do’s

• Before starting Elmiron, read the Medication Guide provided by your pharmacist and consult your healthcare provider if you have any questions. 
• Elmiron is typically taken orally at least 1 hour before or 2 hours after meals, as directed by your healthcare provider, usually 3 times daily. 
• Use Elmiron regularly to get the most benefit from it. To help you remember, take it at the same times each day.
• Tell your healthcare provider if your condition worsens or does not improve after 3 months. Regular monitoring and communication with your healthcare provider are essential for assessing the effectiveness of the medication.
• Elmiron should be used only as prescribed by your healthcare provider, and any changes to the dosage or frequency should be discussed with them.

Don’ts

• Do not increase your dose or take Elmiron more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase. 

Common Side Effects:

• Abnormal liver function tests
• Blood in the stool
• Bruising
• Diarrhea
• Dizziness
• Hair loss
• Headache
• Skin rash
• Nausea
• Abdominal pain

Unusual Side Effects:

• Insomnia
• Worsening mood

Serious Side Effects:

• Eye disorders including maculopathy, visual impairment, and blurred vision
• Recent studies suggest that years-long use of Elmiron may contribute to pigmentary maculopathy

The reported side effects may vary from person to person, and not all individuals may experience these effects. If you are experiencing any of these side effects or have concerns about taking Elmiron, consult your healthcare provider for personalized advice and guidance.

Adverse effects of Elmiron include dizziness and visual disturbances which could affect the ability to drive or use machines. Patients should be advised accordingly.

Patients on long-term therapy with Elmiron should have their complete blood count, APTT, prothrombin time, liver function tests, renal function tests, and serum calcium monitored periodically. Clinical status should also be checked regularly.

Elmiron has a weak anticoagulant effect, which may increase bleeding times. Patients should be reminded of this effect and take precautions to reduce the risk of bleeding.

There haven't been well-controlled studies of Elmiron with pregnant women. Avoid using it when pregnant.

Elmiron can cause changes in the retina of the eye, which can damage vision. Discuss this risk with your healthcare provider before taking Elmiron.

Be aware of these warnings and precautions and consult a healthcare provider for any concerns or questions regarding the medication.