Neoral (Cyclosporine)

Do’s

• Take it exactly as prescribed: Follow your healthcare provider's instructions on dosage and frequency. Neoral is typically taken twice a day, with or without food, but be consistent with your chosen method for each dose.
• Consider weight and medical condition: Dosage is based on your weight, medical condition, lab results, and how you respond to the treatment.
• Avoid grapefruit: Grapefruit can interact with Neoral and increase side effects. Steer clear of it unless your healthcare provider says it's safe.
• Take it regularly: Consistency is key for optimal benefit. Aim to take it at the same times each day.
• Be patient: For rheumatoid arthritis and psoriasis, it may take up to 4 months to experience the full effects of Neoral.
• Report to your healthcare provider: If your condition doesn't improve within the expected timeframe (4-8 weeks for arthritis, 2-4 weeks for psoriasis), or if it worsens, tell your healthcare provider.

Don't

• Don't take more than prescribed. Taking more than recommended can be dangerous.
• Don't skip or forget doses. Skipping doses can disrupt treatment effectiveness.
• Don't switch between taking it with or without food. Maintain consistency.
• Don't consume grapefruit. Avoid grapefruit and grapefruit juice while on Neoral.
• Don'ttop taking it abruptly. Stopping Neoral suddenly can cause health problems. Discuss any concerns with your healthcare provider.

Common side effects:

• Hirsutism (excessive hair growth)
• Hypertension (high blood pressure)
• Increased blood urea nitrogen
• Increased serum creatinine
• Nephrotoxicity
• Tremor
• Acne
• Increased growth of facial or body hair
• Swollen or painful gums
• Diarrhea
• Nausea

Serious side effects that may require immediate medical attention include:

• Mental/mood changes (such as confusion, difficulty concentrating)
• Vision changes
• Problems with speech
• Clumsiness
• Loss of coordination
• Weakness on one side of the body
• Seizures
• Chest pain
• Allergic reaction symptoms: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing
• Liver problems: severe stomach pain, fever, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes)
• Sudden and severe pelvic pain

This is not an exhaustive list, and other side effects may occur. If you experience any unusual or severe side effects while taking Neoral,  contact your healthcare provider for medical advice.

Inform your healthcare provider of any allergies to cyclosporine or its ingredients.

Disclose your medical history to your healthcare provider, especially kidney disease, liver disease, high blood pressure, cancer, skin lesions, radiation treatment, mineral imbalances, infections, high cholesterol/triglycerides, and previous psoriasis treatments (coal tar, methotrexate, radiation, PUVA/UVB light therapy).

Cyclosporine may cause dizziness. Avoid activities requiring alertness (driving, machinery) until you feel safe. Limit alcohol and marijuana use which can worsen dizziness.

Consult your healthcare provider before using cyclosporine if you are pregnant, breastfeeding, or have liver disease or alcohol dependence.

Cyclosporine weakens your immune system, increasing the risk and severity of infections and some cancers (skin cancer, lymphoma). Be aware of and report signs of infection or cancer to your healthcare provider.

Inform your healthcare provider about cyclosporine use before any vaccinations and avoid contact with people who recently received live vaccines.

Limit sun exposure, tanning booths, and sunlamps. Use sunscreen and protective clothing. Avoid phototherapy if directed by your healthcare provider. Psoriasis patients with prior treatments (coal tar, methotrexate, radiation, PUVA/UVB light therapy) have a higher risk for skin cancer. Discuss this risk with your healthcare provider.

Consult your healthcare provider before using potassium supplements or salt substitutes.

Inform your healthcare provider about all medications you take before surgery.

Older adults may be more susceptible to kidney problems or high blood pressure while using cyclosporine.

Cyclosporine should only be used during pregnancy if clearly necessary due to potential harm to the unborn baby. Discuss risks and benefits with your healthcare provider.

Cyclosporine passes into breast milk. Consult your healthcare provider before breastfeeding.

Cyclosporine can increase your risk of high blood pressure and kidney problems. Your healthcare provider will monitor these functions regularly.

Don't switch cyclosporine brands without your healthcare provider's approval due to potential dosage variations.